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ING-056Ingredient Research Profile

Adaptogens

Panax Ginseng (Korean Ginseng)

Also known as: Korean red ginseng · Panax ginseng C.A. Meyer · True ginseng

●●○Moderate Evidence

The original adaptogen. Ginsenosides modulate the stress axis, improve cognitive performance, support immune function, and have emerging evidence for erectile function.

Effective Dose

200–400mg / day

per clinical evidence

Evidence Level

Moderate

Adaptogens

Mechanism

Ginsenoside-mediated HPA and immune modulation, NO upregulation

primary action

Best For

Energy

Cognitive performance, Immune function, Libido

This profile is for informational purposes only and does not constitute medical advice. Consult a qualified healthcare professional before starting any supplementation, especially if you have pre-existing conditions or take medications.

What Is Panax Ginseng (Korean Ginseng)?

Panax ginseng has the longest documented use of any adaptogen — over 2000 years in Traditional Chinese Medicine. Modern research identifies over 150 ginsenosides (triterpenoid saponins) as its primary actives. Korean red ginseng (steamed and dried root) has a different ginsenoside profile and stronger evidence than white ginseng.

How It Works: The Science

Ginsenosides interact with glucocorticoid receptors, sex hormone receptors, and various ion channels. Rg1 ginsenosides activate eNOS (vasodilation, erectile function), while Rb1 ginsenosides have GABA-like CNS effects (calming focus). Panaxosides modulate immune function via NK cell and macrophage activation.

Primary Mechanism

Ginsenoside-mediated HPA and immune modulation, NO upregulation

Evidence-Based Benefits

Improves cognitive performance and reaction time

moderate

Kennedy et al. (2001) — 400mg improved quality of memory and calmness

Reduces mental fatigue and improves working memory

moderate

Reay et al. (2005, 2006) — multiple doses improved sustained attention and working memory

Improves erectile function

moderate

Hong et al. (2002) — Korean red ginseng improved erectile function vs placebo

Supports immune function and reduces infection duration

moderate

McElhaney et al. (2006) — reduced cold and flu severity in elderly

Dosage Guide

Effective Dose

200–400mg / day

200–400mg/day of standardised extract (≥7% ginsenosides). Korean red ginseng root: 1–2g/day. Effects build over weeks of consistent use. May be taken in cycles of 8–12 weeks with rest periods.

Safety Profile & Side Effects

Generally safe. 'Ginseng abuse syndrome' (insomnia, hypertension, diarrhoea) reported at very high doses (>3g/day of crude root). May interact with warfarin and diabetes medications. Avoid with stimulants in hypertension.

Who Should (and Shouldn't) Take It

Best for
EnergyCognitive performanceImmune functionLibido
Who it's for

Those seeking a broad-spectrum cognitive and vitality adaptogen. Particularly useful for older adults experiencing age-related cognitive decline and reduced energy.

Frequently Asked Questions

What is the recommended dose of Panax Ginseng (Korean Ginseng)?

200–400mg/day of standardised extract (≥7% ginsenosides). Korean red ginseng root: 1–2g/day. Effects build over weeks of consistent use. May be taken in cycles of 8–12 weeks with rest periods.

Is Panax Ginseng (Korean Ginseng) safe?

Generally safe. 'Ginseng abuse syndrome' (insomnia, hypertension, diarrhoea) reported at very high doses (>3g/day of crude root). May interact with warfarin and diabetes medications. Avoid with stimulants in hypertension.

How does Panax Ginseng (Korean Ginseng) work?

Ginsenosides interact with glucocorticoid receptors, sex hormone receptors, and various ion channels. Rg1 ginsenosides activate eNOS (vasodilation, erectile function), while Rb1 ginsenosides have GABA-like CNS effects (calming focus). Panaxosides modulate immune function via NK cell and macrophage activation.

Who should take Panax Ginseng (Korean Ginseng)?

Those seeking a broad-spectrum cognitive and vitality adaptogen. Particularly useful for older adults experiencing age-related cognitive decline and reduced energy.

Related Ingredients

Ashwagandha (KSM-66 / Sensoril)Rhodiola RoseaEleuthero (Siberian Ginseng)Tongkat Ali (Eurycoma Longifolia)

Medical Disclaimer

Ingredient profiles are for informational purposes only and do not constitute medical advice. Consult a qualified healthcare professional before starting any supplementation, especially if you have pre-existing conditions or take medications. Full disclaimer →