VOL. I · 2026 · EVIDENCE-LED SUPPLEMENT RESEARCHUSA & GLOBAL EDITION
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ING-121Ingredient Research Profile

Testosterone & Hormonal

Fenugreek Extract

Also known as: Trigonella foenum-graecum · Testofen · Fenugreek seed extract

●●○Moderate Evidence

Steroidal saponins inhibit 5-alpha reductase and aromatase, shifting testosterone metabolism away from DHT and oestrogen — raising free testosterone. Testofen is the most studied patented extract.

Effective Dose

500–600mg / day

per clinical evidence

Evidence Level

Moderate

Testosterone & Hormonal

Mechanism

5-alpha reductase inhibition, aromatase modulation, free testosterone elevation

primary action

Best For

Free testosterone

Libido, Blood sugar, Milk production

This profile is for informational purposes only and does not constitute medical advice. Consult a qualified healthcare professional before starting any supplementation, especially if you have pre-existing conditions or take medications.

What Is Fenugreek Extract?

Fenugreek seeds contain furostanol and spirostanol saponins (including protodioscin) that modulate androgen metabolism. The Testofen brand (standardised to 50% fenuside saponins) has published human RCTs showing increases in free testosterone and sexual function. Fenugreek is also a traditional galactagogue and has blood glucose-lowering properties.

How It Works: The Science

Fenugreek saponins inhibit 5-alpha reductase (which converts testosterone to DHT) and aromatase (which converts testosterone to oestrogen), reducing testosterone clearance and raising free T. They also bind androgen receptors with weak agonist activity. The fibre content (galactomannan) slows glucose absorption, contributing to blood sugar benefits.

Primary Mechanism

5-alpha reductase inhibition, aromatase modulation, free testosterone elevation

Evidence-Based Benefits

Increases free testosterone and sexual function in men

moderate

Steels et al. (2011) — 600mg Testofen/day for 6 weeks improved free T and sexual function

Reduces fasting blood glucose and insulin resistance

moderate

Multiple RCTs — 10–15% reduction in fasting glucose in T2D patients

Supports milk production in breastfeeding women

moderate

Traditional use supported by multiple observational studies

Dosage Guide

Effective Dose

500–600mg / day

500–600mg Testofen (50% fenuside) daily; or 500mg 4-OH-isoleucine-standardised extract for blood glucose effects. General fenugreek seed powder requires 5–10g/day for blood sugar effects.

Safety Profile & Side Effects

Maple-syrup body odour is common and harmless. Hypoglycaemia risk when combined with diabetes medications. Avoid during pregnancy (uterine stimulant effects at high doses). May cause GI upset.

Who Should (and Shouldn't) Take It

Best for
Free testosteroneLibidoBlood sugarMilk production
Who it's for

Men with low-normal testosterone and declining libido, athletes wanting natural testosterone support, and those managing blood sugar.

Frequently Asked Questions

What is the recommended dose of Fenugreek Extract?

500–600mg Testofen (50% fenuside) daily; or 500mg 4-OH-isoleucine-standardised extract for blood glucose effects. General fenugreek seed powder requires 5–10g/day for blood sugar effects.

Is Fenugreek Extract safe?

Maple-syrup body odour is common and harmless. Hypoglycaemia risk when combined with diabetes medications. Avoid during pregnancy (uterine stimulant effects at high doses). May cause GI upset.

How does Fenugreek Extract work?

Fenugreek saponins inhibit 5-alpha reductase (which converts testosterone to DHT) and aromatase (which converts testosterone to oestrogen), reducing testosterone clearance and raising free T. They also bind androgen receptors with weak agonist activity. The fibre content (galactomannan) slows glucose absorption, contributing to blood sugar benefits.

Who should take Fenugreek Extract?

Men with low-normal testosterone and declining libido, athletes wanting natural testosterone support, and those managing blood sugar.

Related Ingredients

Tongkat Ali (Eurycoma Longifolia)Ashwagandha (KSM-66 / Sensoril)Zinc (Bisglycinate / Picolinate)Boron

Medical Disclaimer

Ingredient profiles are for informational purposes only and do not constitute medical advice. Consult a qualified healthcare professional before starting any supplementation, especially if you have pre-existing conditions or take medications. Full disclaimer →