⚖️ Protein Powder Comparison

Dymatize ISO100 vs MyProtein Impact Whey (2026)

Hydrolysed whey isolate vs budget WPC concentrate โ€” what the extra money actually buys you, and who genuinely needs it.

By Jake Reynolds, CISSN · Updated April 2026
ISO100 Hydrolyzed Whey
ISO100 Hydrolyzed Whey
Dymatize
9.0/10
🥇 FitLab Pick
Impact Whey Protein
Impact Whey Protein
MyProtein
8.5/10

At a Glance

Metric ISO100 Hydrolyzed Whey Impact Whey Protein
FitLab Score9.0/108.5/10
Protein per scoop25g21g
Calories110 cal103 cal
Fat0.5g1.9g
Carbohydrates2g2g
LactoseZero (ultrafiltered)Moderate (WPC-80)
Protein type100% Hydrolysed WPIWPC-80
Absorption speedFastest (~30 min)Fast (~55 min)
Price per serving$1.18$0.78 (sale)
Third-party certInformed Choice โœ…None โœ—
Flavours12+80+

Protein Type โ€” Isolate vs Concentrate

The core difference is processing. MyProtein Impact Whey uses WPC-80 โ€” whey protein concentrate at 80% protein purity. ISO100 uses 100% hydrolysed whey protein isolate โ€” further filtered to 90%+ purity, then enzymatically hydrolysed into peptides.

In practical terms: ISO100 has significantly less fat (0.5g vs 1.9g per scoop), zero lactose vs moderate, and faster absorption. For someone tracking macros tightly or cutting for a competition, the cleaner macro profile matters. For someone in a bulk or casual training phase, the WPC macros are negligible.

Lactose โ€” The Most Important Difference

If you have clinically confirmed lactose intolerance (or even just regular GI sensitivity to dairy), this comparison ends here: ISO100. The ultrafiltration process used in WPI production removes lactose completely. WPC-80 retains meaningful amounts.

The scale of global lactose intolerance makes this more important than most gym-goers realise. Estimates suggest 65% of the world population has reduced lactase activity. Most people compensate subconsciously โ€” attributing GI discomfort to 'bad stomach days' rather than their WPC protein shake.

💡 Test your lactose response: Switch to ISO100 for 4 weeks and note any change in bloating, GI comfort, or digestion post-shake. If you notice a significant improvement, you were likely experiencing mild lactose sensitivity โ€” and the ISO100 premium is justified.
⚖️ Jake's Verdict

ISO100 Hydrolyzed Whey wins โ€” but Impact Whey Protein is better for some buyers

ISO100 wins on protein quality, lactose content, absorption speed, and macro purity. Impact Whey wins on cost and flavour variety. The right choice depends entirely on your needs: lactose intolerant โ†’ ISO100 always. Budget-conscious, lactose tolerant โ†’ Impact Whey on sale.

Read ISO100 Hydrolyzed Whey Review → Read Impact Whey Protein Review →

Frequently Asked Questions

Is hydrolysed protein better for muscle building?+

At matched protein doses, no โ€” there is no significant difference in 12-week muscle mass gains between hydrolysed and standard WPI. The hydrolysis advantage is absorption speed, not total muscle built. The faster absorption (30 min vs 55 min peak) matters for twice-daily training athletes, not for those training once daily.

Can lactose intolerant people use Impact Whey?+

Generally no โ€” Impact Whey is WPC-80 which retains significant lactose. Switch to ISO100, Isopure Zero Carb, or a plant protein like Garden of Life Sport which is completely dairy-free.

What is the best ISO100 flavour?+

Fudge Brownie is widely considered the best chocolate protein flavour on the market at any price point. Gourmet Vanilla is the best all-rounder for mixing into coffee, oats, or baking. Birthday Cake is accurate but polarising.

Which has more flavours?+

MyProtein wins by a significant margin โ€” 80+ vs 12+ flavours for ISO100. If flavour variety is important to you, Impact Whey has a clear advantage.

References: Tang JE et al. (2009). Ingestion of whey hydrolysate, casein, or soy protein isolate: effects on mixed muscle protein synthesis at rest and following resistance exercise in young men. J Appl Physiol.
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